Future Medicine

THC Has Potential for Treating Agitation in Alzheimer’s Disease

June 24, 2019 Aging, Agitation, Alzheimer's Disease, Anxiety, Behavior change, Cannabinoids, Cannabis, Cannabis Education, Cannabis Science, Case Study, Cognition, Elderly, Future Medicine, Insomnia, Memory, Nabilone, Stigma, Synthetic Cannabinoids

In a crossover trial of 39 patients with Alzheimer’s disease, treatment with nabilone (a synthetic THC analog) was associated with significant improvement in agitation and, remarkably, cognition. Further studies should examine the effects of both THC and CBD in patients with Alzheimer’s disease because anxiety is common in dementia and may exacerbate agitation.

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Tetrahydrocannabinol Has Potential for Treating Agitation in Alzheimer’s Disease Download

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Analyses of Cannabinoid Signaling in the Immune System Highlights Key Questions, Challenges, and Future Directions

June 24, 2019 Adolescents, Anti-inflammatory properties, Arthritis, Autoimmunity, Behavior change, Cannabinoids, Cannabis, Cannabis Science, CB1, CB2, CBD, Depression, Diabetes, Future Medicine, Neuropathy, Pain, Science, THC

Targeting Cannabinoid Signaling in the Immune System: “High”-ly Exciting Questions, Possibilities, and Challenges

A meta-analysis concerning the role of cannabinoid signaling in immune system regulations revealed current therapeutic benefits, challenges for future research, and exciting new directions. Among the current research, cannabinoids have already been found to suppress inflammation associated with autoimmune diseases, especially in multiple sclerosis, rheumatoid arthritis, Type-1 Diabetes, and Crohn’s Disease. Future cannabis-based therapies aim to improve immune responses to organ donation, bone marrow transplants, and skin grafts. The analysis includes challenges facing future cannabis research such as potential side effects and legal status.

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Targeting Cannabinoid Signaling in the Immune System- “High”-ly Exciting Questions, Possibilities, and Challenges Download

This paper is also stored here: http://bit.ly/31ArGR9 inside the CED Foundation Archive

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Variations in Genes Influences Cannabis’ Acute Effects on Behavior

June 23, 2019 Addiction, Adolescents, Adverse Effects, Anxiety, Behavior change, Cannabinoids, Cannabis, Cannabis Science, CB1, CB2, CBD, Cognition, Cortisol, Future Medicine, Memory, Mental Health, Pain, Science, THC

CNR1 and FAAH variation and affective states induced by marijuana smoking

A recent study has revealed that variations within cannabinoid receptor 1 (CBR1) and fatty acid amide hydrolase (FAAH) influences cannabis’ acute effects on affect. Variations of CBR1 and FAAH are known to be associated with cannabis dependence. The current study now adds that the variations in genes also affect an individual’s behavior when ingesting cannabis. The results of this study provide useful information for understanding an individual’s motivation for marijuana use, as well as risks and associated behaviors.

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CNR1 and FAAH variation and affective states induced by marijuana smoking Download

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Social Responsibility for the Cannabis Industry

June 22, 2019 Business of Cannabis, California, Cannabis News, Financial Projections, Future Medicine, Los Angeles, Social Equity, Social Justice

With an emerging industry that has millions of dollars being fed into it, companies are trying to take social responsibility and operate with the public interest in mind. Things like this can narrow the gap of trust between industry, community, and policymakers, as well as fight stigma. https://nyp.st/2L4lKdp

Prospective analysis of safety and efficacy of medical cannabis in a large, unselected population of patients with cancer

June 22, 2019 Cancer, Cannabinoids, Cannabis, Cannabis Science, CBD, Citizen Science, Future Medicine, History, Science, Survey, THC

In a study of 2,970 cancer patients, researchers determined that cannabis as a palliative treatment seems to be well tolerated, effective and a safe option to help patients cope with cancer-related symptoms.

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Prospective analysis of safety and efficacy of medical cannabis in large unselected population of patients with cancer Download

This paper is also stored here: http://bit.ly/2Fiid7B inside the CED Foundation Archive

Recently Identified Mechanism of Chronic Stress-Induced Pain

June 22, 2019 Addiction, Cannabinoids, Cannabis, Cannabis Science, CB1, CB2, CBD, Cognition, Cortisol, Depression, Future Medicine, History, Mental Health, Pain, Science, Stress, THC

Chronic Stress Is Associated with Pain Precipitation and Elevation in DeltaFosb Expression

Researchers have identified Delta-FosB, an osteosarcoma viral oncogene, as a useful molecular marker of sustained pain. The expression of Delta-FosB is significantly elevated by stress-induced pain, exposing its role in the adaptability of nerves. This study supports theories that Delta-FosB plays an important role in drug addiction, depression, and stress adaptation. The interaction between stress, depression, and pain is something that is not yet well-understood. But, as we learn more about cannabis-based medicine, many of the age-old questions about pain have become much clearer.

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Chronic Stress Is Associated with Pain Precipitation and Elevation in DeltaFosb Expression Download

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Pregnant women are using more cannabis over time

June 21, 2019 Adverse Effects, Cannabinoids, Cannabis Education, Cannabis News, Cannabis Science, CB1, CB2, CBD, Citizen Science, Future Medicine, News, Pregnancy, Regulation, Stigma, THC, Women in Cannabis

Statistics show that in the past 15 years, the number of pregnant women using marijuana, especially in their first trimester, has risen greatly. These numbers may be slightly skewed, but they show the importance of more research being done on the effect of cannabis on pregnant women. https://cnn.it/2WWQV1e

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Home Grows vs Big Marijuana vs Governmental Oversight

June 21, 2019 Cannabis News, Dispensaries, Financial Projections, Future Medicine, History, Illinois, Law, Legislation, New York, Social Equity, Social Justice, Stigma, THC

In light of recent changes and discussion in NY and IL cannabis laws, the right to grow at home has been highly debated. Legislation and “big marijuana” are concerned with black market control, lab testing, and lost tax revenue; many of these concerns are blown out of proportion http://bit.ly/2WSbsUK

Safety and Efficacy of Medical Cannabis in Fibromyalgia

June 21, 2019 Anti-inflammatory properties, Arthritis, Cannabinoids, Cannabis, Cannabis Science, CB1, CB2, CED In The News, Fibromyalgia, Future Medicine, Muscle Pain, Neuropathy, Pain, Science, THC

In a study of 367 patients, researchers investigated the safety and effectiveness of cannabis consumption to treat fibromyalgia symptoms. After treatment with cannabis, pain intensity (scale 0–10) reports reduced from a median of 9.0 to a median of 5.0. Interestingly, patients who had previously used cannabis were more likely to have treatment success, whereas patients who shared concerns about cannabis treatment were more likely to have treatment failure. A patient’s mindset can directly affect their treatment outcome.

At CED Clinic, we use the power of education to help patients feel comfortable and confident with their treatment plan.

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Safety and Efficacy of Medical Cannabis in Fibromyalgia Download

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Profile of Dr Caplan, Dr Grinspoon, CED Clinic, and modern Medical Cannabis in Alcoholism & Drug Abuse Weekly

June 21, 2019 Addiction, Alcohol, Anxiety, Behavior change, Cannabis, Cannabis Education, Cannabis News, CED Clinic, CED In The News, Dispensaries, Dr Caplan, Dr Grinspoon, Future Medicine, Illicit Drug Use, Law, Legislation, Massachusetts, Politics, Social Equity, Social Justice, THC

The esteemed medical periodical, Alcoholism & Drug Abuse Weekly, takes a closer look at modern medical cannabis with Dr Grinspoon and I. Our discussion brings an insider’s look at how the system operates, from clinic to dispensary, the dynamic changes we’ve already seen and highlights some of the changes to come. Included are The Role of Medicine, The Ethics of doctors in business, The Patient Experience, Physician’s Support, Growing the Plant, and a sit-down with a local dispensary.

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ADAW-June-24-2019 Download

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