Future Medicine

Guidelines for Canada’s cannabis edibles tight, but also vague

https://vancouversun.com/news/local-news/guidelines-for-canadas-cannabis-edibles-tight-but-also-vague

Months after the decision to legalize cannabis, Canadian lawmakers work to regulate the packaging and advertising of cannabis products. The new guidelines forbid the mixing of alcohol and THC and also ensure that products are not “appealing to a young person.”

Benjamin Caplan, MDGuidelines for Canada’s cannabis edibles tight, but also vague
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Tetrahydrocannabinol and cannabidiol as potential curative agents for cancer. A critical examination of the preclinical literature.

According to multiple mouse-models, THC administered directly into cancerous tumors produces a reduction in tumor sizes.

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This paper is also stored here:   http://bit.ly/2FfKagk      inside the CED Foundation Archive

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Benjamin Caplan, MDTetrahydrocannabinol and cannabidiol as potential curative agents for cancer. A critical examination of the preclinical literature.
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CBD Overcomes Resistance to current treatment of Human Colorectal Cancer Cells

Oxaliplatin is the most commonly used drug to treat colorectal cancer (CRC), but patients often develop resistance to it. So, researchers conducted a study to determine the effect of CBD in overcoming oxaliplatin resistance in CRC cells. They found that elevated NOS3 phosphorylation is an essential part of the development of oxaliplatin resistance, and CBD successfully decreased NOS3 phosphorylation. This effect resulted in cells overcoming oxaliplatin resistance, which suggests that CBD could be a new strategy to treat colorectal cancer. 

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This paper is also stored here:    http://bit.ly/2IwfVn9     inside the CED Foundation Archive

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Benjamin Caplan, MDCBD Overcomes Resistance to current treatment of Human Colorectal Cancer Cells
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Cannabinoid Receptors Working with Opioid Receptors

The locus coeruleus is a spot in the human brainstem that is integral to our responses to stress, panic, wakefulness, and sleep-wake transitions. Both the cannabinoid receptors and opioid receptors in the locus coeruleus have a synergistic relationship that, once the medical system begins to incorporate more education about cannabinoids, just might change how physicians prescribe pain medication. The interactions of the two receptor types provide a mechanism that could easily and conveniently improve pain control, provide treatments for addiction, and will likely aid those experiencing symptoms of withdrawal. Research focusing on the treatment of opioid addiction with cannabis is ongoing… but hindered by the legal status of cannabis.

View this review (yellow link) or download:

This paper is also stored here:     http://bit.ly/2MMeYeK    inside the CED Foundation Archive

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Benjamin Caplan, MDCannabinoid Receptors Working with Opioid Receptors
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Cannabis sales could hit $15 billion globally this year

Fueled by CBD product sales and Canada’s recent legalization of marijuana, the world’s cannabis market could total $14.9 billion in 2019, up 36% from 2018, according to a new report released Thursday.

https://www.cnn.com/2019/06/20/tech/cannabis-industry-15-billion/index.html

Benjamin Caplan, MDCannabis sales could hit $15 billion globally this year
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Lawmakers explore easing rules on small cannabis businesses

On Wednesday, House lawmakers explored efforts to ease rules and boost small business owners in the legal cannabis industry. During the hearing before the House Committee, workers from the cannabis industry discussed the financial and legal obstacles they face while running their small businesses.

https://thehill.com/policy/finance/449419-lawmakers-explore-easing-rules-on-small-cannabis-businesses

Benjamin Caplan, MDLawmakers explore easing rules on small cannabis businesses
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Dispensaries that launched cannabis in West Hollywood can continue to sell recreational pot… for now

On Monday, the LA City Council decided to allow the city’s original 4 dispensaries to maintain temporary licenses to sell recreational marijuana. The dispensaries were set up in 2003, but in 2016, the council decided that the stores should compete with nearly 100 other dispensaries for just 8 licenses. None of the original stores secured top 8 spots, so now their owners fight to maintain the right to sell cannabis until the 8 other stores open shop.

https://www.latimes.com/local/lanow/la-me-ln-west-hollywood-original-dispensaries-vote-20190618-story.html

Benjamin Caplan, MDDispensaries that launched cannabis in West Hollywood can continue to sell recreational pot… for now
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New York’s Adult-Use Cannabis Legalization Bill is Dead

Despite a poll showing that the majority of New Yorkers support legalization, lawmakers could not agree on a handful of key components of the Marijuana Regulation and Taxation Act (MRTA), thus deciding not to pass the bill.

https://www.leafly.com/news/politics/new-yorks-adult-use-cannabis-legalization-bill-is-dead

Benjamin Caplan, MDNew York’s Adult-Use Cannabis Legalization Bill is Dead
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Safety and Efficacy of Medical Cannabis in Fibromyalgia

Another study with promising results for the use of cannabis to treat chronic pain and fibromyalgia-related symptoms. A large majority of participants reported improved sleep, depression-related symptoms, quality of life and over 20% stopped or reduced the dosage of opioids. https://prn.to/2KXUQUe

View this review (yellow link) or download:

This paper is also stored here:     http://bit.ly/2WWLyz6    inside the CED Foundation Archive

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Benjamin Caplan, MDSafety and Efficacy of Medical Cannabis in Fibromyalgia
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Dronabinol: antileukemic activity in acute lymphoblastic and myeloid leukemia with lymphoid differentiation patterns

Study provides rigorous data to support clinical evaluation of THC as a low-toxic therapy option in acute leukemia patients. In related work, full-spectrum, natural derivatives of cannabis may work more effectively than their pharmaceutical counterparts.

View this review (yellow link) or download:

This paper is also stored here:    http://bit.ly/2KVVXnD     inside the CED Foundation Archive

To explore related information, click the keywords below:

Benjamin Caplan, MDDronabinol: antileukemic activity in acute lymphoblastic and myeloid leukemia with lymphoid differentiation patterns
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