CBD

Colorado Medical Patients losing priority & Rights

In Colorado, medical patients are losing priority and rights at dispensaries due to expiring laws, and dispensaries are focusing on rec. cannabis for fiscal purposes. Up to legislation to maintain focus on medical cannabis, which would be the path to federal legalization of cannabis. http://bit.ly/2Ylmamw

Benjamin Caplan, MDColorado Medical Patients losing priority & Rights
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How to store cannabis

If stored properly, cannabis can last up to two years.
We are starting to see ground-breaking technology rising in the industry, including filtration of humidity built into packaging, as well as permeable membranes that support the wise guarding of both hydration and terpene/flavonoid concentration.

https://www.leafly.com/news/cannabis-101/how-long-is-my-cannabis-good-for-leaflys-guide-to-storing-cannabi

Benjamin Caplan, MDHow to store cannabis
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Medical cannabis doctors left to handle “backlash” from patients over lack of availability

Though UK doctors have been able to prescribe cannabis since November 2018, very few prescriptions have been issued, because most forms of medical cannabis have not been approved by the government.

In response to thousands of disappointed patients, the House of Commons Health and Social Care Committee called for immediate clinical trials focusing on the treatment of intractable childhood epilepsy. 

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This paper is also stored here:   http://bit.ly/2XXYrEJ      inside the CED Foundation Archive

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Benjamin Caplan, MDMedical cannabis doctors left to handle “backlash” from patients over lack of availability
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CB1 and CB2 receptors play differential roles in early zebrafish locomotor development

Scientists found that blocking CB1 receptors and CB2-receptors in young zebrafish resulted in morphological deficits, reductions in heart rate, and non-inflated swim bladders. These findings indicate that the endocannabinoid system is pivotal to the development of the locomotor system in zebrafish, and that disturbances to the endocannabinoid system in early life may have detrimental effects.

The translation of these effects to humans is obviously not direct, but it is important for science to learn about safety and expected effects, to examine how chemistry interacts in petri dishes, how basic organic/animal functions are impacted in a living thing, and when the time is appropriate, to then assess any effects in humans

View this review (yellow link) or download:

This paper is also stored here:   http://bit.ly/2YfykgI      inside the CED Foundation Archive

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Benjamin Caplan, MDCB1 and CB2 receptors play differential roles in early zebrafish locomotor development
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Do-it-Yourself Cannabis-infused lubricants

Cannabis-infused lubricant can increase blood flow for men and create full-body experiences for women. Find out how to make your own infused lube at home with this video tutorial!

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Benjamin Caplan, MDDo-it-Yourself Cannabis-infused lubricants
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Video: The Endocannabinoid System

A simplified overview of the human side of the human-cannabis interaction system!

Built from the growing mountain of literature inside the CED Foundation Medical Cannabis Archive

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Benjamin Caplan, MDVideo: The Endocannabinoid System
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Video: Do-It-Yourself Cannabis Tinctures

One of the terrific realities of modern Cannabis is that it is possible, and often quite simple, to make effective products at home. With suitable education and access to testing facilities, the soil, nutrients, and plant growth can be supported at home, lab-tested for make-up and potency, as well as safety-checked for potential microscopic contaminants, and ultimately, individualized medicine can be created right at home!

Here is a sample instructional for just one way that cannabis tincture can be made at home. There are countless others and hopefully, many that are yet to be discovered!

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Benjamin Caplan, MDVideo: Do-It-Yourself Cannabis Tinctures
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Hangovers Resulting from Drinking Negatively Impact Everyday Memory

Alcohol Hangover Has Detrimental Impact Upon Both Executive Function and Prospective Memory

A recent study revealed that alcohol hangovers negatively impact everyday memory, specifically executive function (EF) and prospective memory (PM). EF and PM are cognitive functions that underpin everyday memory; things such as remembering an appointment or where you placed your keys. Participants of the study who suffered from hangovers were able to recall significantly fewer items from memory tasks than their peers. The findings of this study may prove useful when looking into how alcohol and cannabis interact with patients.

View this review (yellow link) or download:

This paper is also stored here:     http://bit.ly/2WBUb1Y    inside the CED Foundation Archive

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Benjamin Caplan, MDHangovers Resulting from Drinking Negatively Impact Everyday Memory
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Genes in the Endocannabinoid and Opioid Systems may Provide Biomarkers of Obesity

Title: Preclinical and Clinical Evidence for a Distinct Regulation of Mu Opioid and Type 1 Cannabinoid Receptor Genes Expression in Obesity

Researchers have recently found that alterations of the type 1 cannabinoid receptor gene (CNR1) and mu opioid receptor gene (OPRM1)  contribute to the development of obesity. This phenomenon was shown in rat models who were given a high-fat diet and humans currently dealing with obesity. Due to the possibility of the up-regulation of CNR1 and OPRM1 providing a mechanism for developing the obesity phenotype, those two genes could serve as biomarkers for obesity. Fortunately, the up-regulation of CNR1 and OPRM1 is reversible and may also provide a target for combatting obesity and encouraging weight loss in obese individuals. 

Highlighted here are the interactions of the endocannabinoid and opioid systems. Contradictory evidence concerning the interaction of the two systems has come out in recent years making it difficult to come to any conclusions. The endocannabinoid system has been thought to provide a safe and effective method for combatting the opioid crisis. Opioids are highly addictive and dangerous, but they are an efficient way to minimize pain which has kept them in mainstream medicine. Opioids have led to countless overdoses in recent decades causing researchers to search for a more ethical option for pain relief. Cannabis has a much better safety profile, poses no risk of overdose, and offers a welcome change of pace to traditional choices. Conclusive research is still needed to confirm, and reconfirm the details.

View this review (yellow link) or download:

This paper is also stored here:    http://bit.ly/2xOhoPE     inside the CED Foundation Archive

Benjamin Caplan, MDGenes in the Endocannabinoid and Opioid Systems may Provide Biomarkers of Obesity
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