Cannabinoids

Evidence for Therapeutic Benefits of Cannabidiol, Including Treatment of Ischemic Strokes

June 17, 2019 Adolescents, Adverse Effects, Alzheimer's Disease, Anti-inflammatory properties, Autoimmunity, Behavior change, Cannabinoids, Cannabis, Cannabis Science, CB1, CB2, CBD, Cognition, Concussion, Elderly, Future Medicine, Heavy Use, Insomnia, Memory, Mental Health, Neuropathy, Pain, Stigma, THC

Therapeutic Potential of Non-Psychotropic Cannabidiol in Ischemic Stroke

Cannabidiol (CBD) has a unique therapeutic profile as it has a cannabinoid receptor-independent mechanism, limited side-effects, and patients do not seem to develop an insurmountable tolerance. Research currently focussed on the therapeutic benefits of CBD has demonstrated long-lasting neuroprotective properties against global and focal ischemic injury, such as ischemic stroke. This piece points to CBD as a major component of cannabis-based medicine as a non-psychoactive component. Further research is needed to evaluate the full clinical capabilities of CBD, including its neuroprotective effect.

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The US patent on Cannabinoids as Antioxidants and Neuroprotectants, from 1999: https://patents.google.com/patent/US6630507B1/en

This paper is also stored here: http://bit.ly/2L0PBn3 inside the CED Foundation Archive

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Researchers Look to CBD and THC for the Treatment of Chronic Pain

June 17, 2019 Adverse Effects, Arthritis, Behavior change, Cannabinoids, Cannabis, Cannabis Science, CB1, CB2, CBD, Future Medicine, Pain, Products, Science

Efficacy and safety of cannabidiol followed by an open-label add-on of tetrahydrocannabinol for the treatment of chronic pain in patients with rheumatoid arthritis or ankylosing spondylitis: protocol for a multicentre, randomized, placebo-controlled study

Current researchers have proposed a study protocol that would expose any possible benefits of cannabidiol (CBD) and tetrahydrocannabinol (THC) for the treatment of chronic pain in patients suffering from rheumatoid arthritis (RA) and ankylosing spondylitis (AS). This new study hopes to identify how medical cannabis affects pain and cognitive function in RA and AS and provide evidence that cannabis-based pain medication is an alternative to opioids with fewer risks.

This paper is also stored here: http://bit.ly/2Fb08s5 inside the CED Foundation Archive

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The Education of Dispensary Staff is Varied and Lacks Regulation

June 17, 2019 Adolescents, Anti-inflammatory properties, Anxiety, Arthritis, Behavior change, Cannabinoids, Cannabis, Cannabis Education, Cannabis News, CBD, Citizen Science, Depression, Dispensaries, Elderly, Future Medicine, History, Legislation, Mental Health, Mood, Neuropathy, Obesity, Pain, Pediatrics, Politics, Regulation, Science, Social Equity, Social Justice, Stigma, THC, Withdrawal, Women in Cannabis

Training and Practices of Cannabis Dispensary Staff

How much medical training does your local budtender possess? An online survey sent to medical marijuana dispensary staff reported only 55% of staffers had any formal training for their position, with 20% reporting some background in medical/scientific training. The analysis reported that many among the dispensary staff are recommending cannabis choices that are consistent with current evidence, but some are recommending strains that are either ineffective or exacerbate a patient’s condition. The findings of this study stress the importance of consistent and well-regulated training of dispensary staff.

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This paper is also stored here: http://bit.ly/2FfJNSC inside the CED Foundation Archive

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A Call for Physicians to Embrace Medicinal Cannabis as a Virtuoso of Prudence

June 17, 2019 Addiction, Adverse Effects, Anxiety, Behavior change, Cannabinoids, Cannabis, Cannabis Education, Cognition, Future Medicine, History, Regulation, Social Justice

The Prescription of Medicinal Cannabis and the Virtue of Prudence: Without Phobia(S) Nor Philia(S)

A passionate physician shared his opinion on prescribing patients medicinal cannabis, promoting its use in accordance with the virtue of prudence. The piece implores physicians to identify the medicinal benefits of cannabis and embrace its side effects without fear. Medicinal cannabis has its place among prescriptions with “respect for leges artis” as long as the decision to recommend cannabis is the result of an ethical-clinically based decision.

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This paper is also stored here: http://bit.ly/2Ff3mLc inside the CED Foundation Archive

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Organ Donors can Safely Consume Cannabis

June 16, 2019 Adverse Effects, Aging, Cannabinoids, Cannabis, Cannabis Science, Cannabis Use Disorder (CUD), CBD, Cocaine, Elderly, Future Medicine, Heavy Use, Illicit Drug Use, Occasional Use, Opiates, Products, Science

Effects of Drug Abuse, Smoking and Alcohol on Donor Hearts and Lungs

A review article that discusses how drug use can affect donor organs has revealed that receiving organs, such as a heart or lungs, from a donor who has used cannabis does not add risk to the procedure. A careful assessment of any donor organ should still be conducted, but having a history of cannabis use does not prevent someone from safely donating.

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Effects of Drug Abuse, Smoking and Alcohol on Donor Hearts and Lungs Download

This paper is also stored here: http://bit.ly/2KPxsIx inside the CED Foundation Archive

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High-potency cannabis and incident psychosis: correcting the causal assumption

June 15, 2019 Adverse Effects, Anxiety, Behavior change, Cannabinoids, Cannabis, Cannabis Education, Cannabis News, CB1, CB2, CBD, Cognition, DSM-5, Hypomania, Mental Health, Psychosis, Schizophrenia, THC

Scientists offer a strong counter-position to the belief that cannabis causes psychosis, pointing out the difference between correlation and causation. They argue that smoke exposure from any source (including cigarettes) could explain the reported link between cannabis and psychosis.

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High-potency cannabis and incident psychosis- correcting the causal assumption Download

This paper is also stored here: http://bit.ly/2WHtDr8 inside the CED Foundation Archive

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Treating insomnia with cannabis

June 14, 2019 Cannabinoids, Cannabis, Cannabis News, Cannabis Science, CBD, Future Medicine, Insomnia, REM Sleep, Science, Sleep, Sleep Apnea, THC

Many people use cannabis to treat insomnia, as THC has proven effects. What about CBD? There are no clear, incontrovertible studies, and effects differ by the user, but there are promising results. More noticeably, certain terpenes have been shown to be quite effective, for example, Myrcene. http://bit.ly/2F9PXUp

New Extraction Methods for “Polyphenols” Benefits Future Research

June 14, 2019 Anti-inflammatory properties, Cannabinoids, Cannabis, Cannabis Education, Cannabis Science, CB1, CB2, CBD, Diabetes, Extraction, Flavonoids, Future Medicine, Obesity, Processing, Science, Terpenes

Citrus peels waste as a source of value-added compounds- extraction and quantification of bioactive polyphenols

A recent study has exposed a more efficient, sustainable, and economically viable extraction method for polyphenols (specific active chemical compounds) from citrus peels. One such polyphenol is Naringin, a flavonoid present in lemon peels, which has been hypothesized to have anti-inflammatory and antioxidant effects, as well as, potentially, to help treat obesity. This new extraction method will allow researchers to discover more definite therapeutic effects of polyphenols in citrus peels.

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Citrus peels waste as a source of value-added compounds- extraction and quantification of bioactive polyphenols Download

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Cannabidiol (CBD) as an Adjunctive Therapy in Schizophrenia: A Multicenter Randomized Controlled Trial

June 14, 2019 Anxiety, Behavior change, Cannabinoids, Cannabis, Cannabis Science, CB1, CB2, CBD, DSM-5, Future Medicine, Mental Health, Placebo-Controlled, Science

A 2018 study showed that, for patients with schizophrenia, adding CBD to ongoing antipsychotic treatment reduced psychotic activity, as compared to placebo add-on