All posts tagged: History of Cannabis

In MA, despite being state-legal, FDA says CBD cannot be added to food or dietary supplements. What now?

MA effectively outlawed the sale of any food products with CBD or products which make therapeutic claims. This is the result of FDA saying that CBD cannot be added to food or dietary supplements. In a state where cannabis is legally accessible, consumers and hemp farmers are very unhappy. What do you think? http://bit.ly/2IOtTRm

Benjamin Caplan, MDIn MA, despite being state-legal, FDA says CBD cannot be added to food or dietary supplements. What now?
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Cannabis Cafes coming to MA

Massachusetts has come one step closer to a pilot program involving cannabis cafes across the state. This will also bring about more licenses for cannabis delivery and social consumption, as a less capital-intensive option for entrepreneurs to enter the industry. http://bit.ly/2IOjOUz

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Benjamin Caplan, MDCannabis Cafes coming to MA
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Case Studies Reveal Difficulties in Differences between State Cannabis Laws

Crossing the Line: Care of a Pediatric Patient with Intractable Seizures and Severe Neuropathic Pain in Absence of Access to Medical Marijuana

A recent case report discussing a six-year-old patient suffering from a seizure disorder has exposed the difficulty is receiving treatment across state lines. The patient was prescribed medical marijuana that alleviated the severity and duration of her seizures but was weaned off that medication when traveling to Nebraska for a therapeutic surgery due to the legal status in the state. This case study exposes the difficulty of treating patients across the country due to the legal variability of cannabis across states.  

An interesting question brought up in this case study is how to handle palliative care in the absence of opioids and without synthetic products. A combination of massage, essential oils, and salt light therapies were able to compensate for medical marijuana, but not without great effort. Natural therapies like the ones administered here are costly and highlight the simplicity and effectiveness of medicinal cannabis.

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This paper is also stored here:   http://bit.ly/2IxPoWN      inside the CED Foundation Archive

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Benjamin Caplan, MDCase Studies Reveal Difficulties in Differences between State Cannabis Laws
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Characteristics of Canadians likely to try or increase cannabis use following legalization for non-medical purposes

In October 2018, recreational cannabis became legal in Canada. And in 2019, researchers asked nearly 20 thousand Canadians over the age of 15 about their cannabis habits. The survey found that 1 in 5 Canadians plan on trying or increasing cannabis use following legalization for non-medical purposes, particularly those who are younger, who have used cannabis in the past 3 months, and who have a higher income. To ensure responsible cannabis use and informed decision-making, clinicians and policy-makers should pay close attention to these higher risk populations.

View this review (yellow link) or download:

This paper is also stored here:   http://bit.ly/2Lfduay      inside the CED Foundation Archive

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Benjamin Caplan, MDCharacteristics of Canadians likely to try or increase cannabis use following legalization for non-medical purposes
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Complex Genetics Underlie Cannabinoid Production

Cannabinoid Inheritance Relies on Complex Genetic Architecture

Researchers have recently attempted to discover the genetic basis of cannabinoid production within cannabis plants, finding a complex genetic architecture. This study highlights the lack of knowledge surrounding cannabis cultivation, suggesting current producers record the phenotypic and genetic crosses they breed so that the community can further research the cannabinoids produced. Specifying which genetic profiles match up to the ratio of cannabinoids produced will benefit mass production and medical research.

The introduction of this article focuses heavily on the ratio of ∆-9-tetrahydrocannabinol to cannabidiol, yet there are therapeutic benefits associated with all of the other cannabinoids as well as flavonoids and terpenes produced by the plant. Multiple chemical components of cannabis strains have yet to be fully explored and preliminary findings warrant the same amount of attention in order to develop various therapies.

View this review (yellow link) or download:

This paper is also stored here:   http://bit.ly/2L3PeIl      inside the CED Foundation Archive



Benjamin Caplan, MDComplex Genetics Underlie Cannabinoid Production
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Recently Identified Mechanism of Chronic Stress-Induced Pain

Chronic Stress Is Associated with Pain Precipitation and Elevation in DeltaFosb Expression

Researchers have identified Delta-FosB, an osteosarcoma viral oncogene, as a useful molecular marker of sustained pain. The expression of Delta-FosB is significantly elevated by stress-induced pain, exposing its role in the adaptability of nerves. This study supports theories that Delta-FosB plays an important role in drug addiction, depression, and stress adaptation. The interaction between stress, depression, and pain is something that is not yet well-understood. But, as we learn more about cannabis-based medicine, many of the age-old questions about pain have become much clearer.

View this review (yellow link) or download:

This paper is also stored here:   http://bit.ly/31A7Y86      inside the CED Foundation Archive

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Benjamin Caplan, MDRecently Identified Mechanism of Chronic Stress-Induced Pain
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Home Grows vs Big Marijuana vs Governmental Oversight

In light of recent changes and discussion in NY and IL cannabis laws, the right to grow at home has been highly debated. Legislation and “big marijuana” are concerned with black market control, lab testing, and lost tax revenue; many of these concerns are blown out of proportion http://bit.ly/2WSbsUK

Benjamin Caplan, MDHome Grows vs Big Marijuana vs Governmental Oversight
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Public Cannabis Consumption Now Allowed In Colombia… Is Full Marijuana Legalization Next?

This week, Colombia’s Constitutional Court overruled a ban on the public consumption of cannabis. Now, citizens wonder if the government will soon legalize recreational cannabis in addition to the already-legal medical cannabis. 

https://www.forbes.com/sites/javierhasse/2019/06/19/colombia-public-cannabis-consumption/#22612e3229e9

Benjamin Caplan, MDPublic Cannabis Consumption Now Allowed In Colombia… Is Full Marijuana Legalization Next?
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Cannabis sales could hit $15 billion globally this year

Fueled by CBD product sales and Canada’s recent legalization of marijuana, the world’s cannabis market could total $14.9 billion in 2019, up 36% from 2018, according to a new report released Thursday.

https://www.cnn.com/2019/06/20/tech/cannabis-industry-15-billion/index.html

Benjamin Caplan, MDCannabis sales could hit $15 billion globally this year
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Lawmakers explore easing rules on small cannabis businesses

On Wednesday, House lawmakers explored efforts to ease rules and boost small business owners in the legal cannabis industry. During the hearing before the House Committee, workers from the cannabis industry discussed the financial and legal obstacles they face while running their small businesses.

https://thehill.com/policy/finance/449419-lawmakers-explore-easing-rules-on-small-cannabis-businesses

Benjamin Caplan, MDLawmakers explore easing rules on small cannabis businesses
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