All posts tagged: Behavior Change

Cost-effectiveness of treating pediatric drug-resistant epilepsy

June 25, 2019 Adolescents, Behavior change, Business of Cannabis, Cannabis Science, Financial Projections, Pediatrics, Products, Seizure / Epilepsy, Social Equity, Survey

Cannabis-based treatments may reduce seizures among children with drug-resistant epilepsy, but are these treatments cost-effective?

Economic evaluations of cannabis treatments are needed, and they should address issues including weight-gain over time, switching or discontinuation of treatments, the effectiveness of interventions, and long-term success, beyond the duration of available clinical studies.

Decision Models for Assessing the Cost-Effectiveness of Treatments for Pediatric Drug‑Resistant Epilepsy- A Systematic Review of Economic Evaluations.pdf Download

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Video: Cannabis and Multiple Sclerosis

June 24, 2019 Adverse Effects, Aging, Anti-inflammatory properties, Anxiety, Behavior change, Cannabinoids, Cannabis, Cannabis Education, Cannabis Science, CB1, CB2, CBD, CED Clinic, Dr Caplan, Future Medicine, Insomnia, Multiple Sclerosis, Muscle Pain, Neuropathy, Pain, Science, Sleep, Stigma, THC, Video

A 2019 literature review summarizes the findings on cannabis use for patients with multiple sclerosis. Cannabis has been shown to aid a number of symptoms associated with multiple sclerosis, including chronic pain, spasticity, and problems with sleep. To learn more, check out our video adaptation below:

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Cannabis and Multiple Sclerosis Download

This paper is also stored here: http://bit.ly/2IJAqNz inside the CED Foundation Archive

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Cannabis constituent synergy in a mouse neuropathic pain model

June 24, 2019 Anti-inflammatory properties, Anxiety, Autoimmunity, Behavior change, Cannabinoids, Cannabis Education, Cannabis Science, CB1, CB2, CBD, Future Medicine, Muscle Pain, Neuropathy, Pain, Science, THC

In a mice-model study, researchers found that low dose THC:CBD might successfully treat neuropathic pain.

Neuropathic pain is pain caused by damage to the somatosensory nervous system. Neuropathic pain may be associated with abnormal sensations or pain from normally non-painful stimuli, for example, Phantom Limb Syndrome.

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Cannabis constituent synergy in a mouse neuropathic pain model Download

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THC Has Potential for Treating Agitation in Alzheimer’s Disease

June 24, 2019 Aging, Agitation, Alzheimer's Disease, Anxiety, Behavior change, Cannabinoids, Cannabis, Cannabis Education, Cannabis Science, Case Study, Cognition, Elderly, Future Medicine, Insomnia, Memory, Nabilone, Stigma, Synthetic Cannabinoids

In a crossover trial of 39 patients with Alzheimer’s disease, treatment with nabilone (a synthetic THC analog) was associated with significant improvement in agitation and, remarkably, cognition. Further studies should examine the effects of both THC and CBD in patients with Alzheimer’s disease because anxiety is common in dementia and may exacerbate agitation.

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Tetrahydrocannabinol Has Potential for Treating Agitation in Alzheimer’s Disease Download

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Analyses of Cannabinoid Signaling in the Immune System Highlights Key Questions, Challenges, and Future Directions

June 24, 2019 Adolescents, Anti-inflammatory properties, Arthritis, Autoimmunity, Behavior change, Cannabinoids, Cannabis, Cannabis Science, CB1, CB2, CBD, Depression, Diabetes, Future Medicine, Neuropathy, Pain, Science, THC

Targeting Cannabinoid Signaling in the Immune System: “High”-ly Exciting Questions, Possibilities, and Challenges

A meta-analysis concerning the role of cannabinoid signaling in immune system regulations revealed current therapeutic benefits, challenges for future research, and exciting new directions. Among the current research, cannabinoids have already been found to suppress inflammation associated with autoimmune diseases, especially in multiple sclerosis, rheumatoid arthritis, Type-1 Diabetes, and Crohn’s Disease. Future cannabis-based therapies aim to improve immune responses to organ donation, bone marrow transplants, and skin grafts. The analysis includes challenges facing future cannabis research such as potential side effects and legal status.

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Targeting Cannabinoid Signaling in the Immune System- “High”-ly Exciting Questions, Possibilities, and Challenges Download

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Variations in Genes Influences Cannabis’ Acute Effects on Behavior

June 23, 2019 Addiction, Adolescents, Adverse Effects, Anxiety, Behavior change, Cannabinoids, Cannabis, Cannabis Science, CB1, CB2, CBD, Cognition, Cortisol, Future Medicine, Memory, Mental Health, Pain, Science, THC

CNR1 and FAAH variation and affective states induced by marijuana smoking

A recent study has revealed that variations within cannabinoid receptor 1 (CBR1) and fatty acid amide hydrolase (FAAH) influences cannabis’ acute effects on affect. Variations of CBR1 and FAAH are known to be associated with cannabis dependence. The current study now adds that the variations in genes also affect an individual’s behavior when ingesting cannabis. The results of this study provide useful information for understanding an individual’s motivation for marijuana use, as well as risks and associated behaviors.

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CNR1 and FAAH variation and affective states induced by marijuana smoking Download

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Vaping cannabis among adolescents: prevalence and associations with tobacco use from a cross-sectional study in the USA

June 21, 2019 Adolescents, Behavior change, Cannabis, Cannabis News, Cannabis Science, Citizen Science, Heavy Use, Illicit Drug Use, Pediatrics, Stigma, THC, Vaping

Out of 2,835 high school students from North Carolina, 272 students (or 9.6%) reported ever vaping cannabis. Interestingly, the odds of ever vaping cannabis were significantly higher among males (11.0%) compared with females (8.2%), and significantly higher among non-Hispanic white students (11.3%) compared with non-Hispanic black students (5.0%).

It’s clear that white males are the most likely to have ever vaping cannabis. Why might minority students engage less with recreational drug use?

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Vaping cannabis among adolescents- prevalence and associations with tobacco use from a cross-sectional study in the USA Download

This paper is also stored here: http://bit.ly/2L6zYdv inside the CED Foundation Archive

Profile of Dr Caplan, Dr Grinspoon, CED Clinic, and modern Medical Cannabis in Alcoholism & Drug Abuse Weekly

June 21, 2019 Addiction, Alcohol, Anxiety, Behavior change, Cannabis, Cannabis Education, Cannabis News, CED Clinic, CED In The News, Dispensaries, Dr Caplan, Dr Grinspoon, Future Medicine, Illicit Drug Use, Law, Legislation, Massachusetts, Politics, Social Equity, Social Justice, THC

The esteemed medical periodical, Alcoholism & Drug Abuse Weekly, takes a closer look at modern medical cannabis with Dr Grinspoon and I. Our discussion brings an insider’s look at how the system operates, from clinic to dispensary, the dynamic changes we’ve already seen and highlights some of the changes to come. Included are The Role of Medicine, The Ethics of doctors in business, The Patient Experience, Physician’s Support, Growing the Plant, and a sit-down with a local dispensary.

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ADAW-June-24-2019 Download

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Cannabinoid Receptors Working with Opioid Receptors

June 21, 2019 Addiction, Adolescents, Anxiety, Behavior change, Cannabinoids, Cannabis, Cannabis Science, CB1, CB2, CBD, Cognition, Future Medicine, Memory, Neuropathy, Opiates, Science

The locus coeruleus is a spot in the human brainstem that is integral to our responses to stress, panic, wakefulness, and sleep-wake transitions. Both the cannabinoid receptors and opioid receptors in the locus coeruleus have a synergistic relationship that, once the medical system begins to incorporate more education about cannabinoids, just might change how physicians prescribe pain medication. The interactions of the two receptor types provide a mechanism that could easily and conveniently improve pain control, provide treatments for addiction, and will likely aid those experiencing symptoms of withdrawal. Research focusing on the treatment of opioid addiction with cannabis is ongoing… but hindered by the legal status of cannabis.

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Characterization of cannabinoid-1 receptors in the locus coeruleus relationship with mu-opioid receptors Download

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Safety and Efficacy of Medical Cannabis in Fibromyalgia

June 20, 2019 Anxiety, Behavior change, Bipolar Disorder, Cannabinoids, Cannabis, Cannabis News, Cannabis Science, CBD, Depression, Fibromyalgia, Future Medicine, Science, THC

Another study with promising results for the use of cannabis to treat chronic pain and fibromyalgia-related symptoms. A large majority of participants reported improved sleep, depression-related symptoms, quality of life and over 20% stopped or reduced the dosage of opioids. https://prn.to/2KXUQUe

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