Science

Countering the Modern Metabolic Disease Rampage With Ancestral Endocannabinoid System Alignment

June 11, 2019 Cannabinoids, Cannabis, Cannabis News, Cannabis Science, CB1, Diabetes, Future Medicine, History, News, Science, Social Justice

Cannabinoid receptors, located throughout the body, are involved in a variety of physiological processes (including appetite, mood, etc.). A 2019 study shows that blocking CB1Rs (cannabinoid receptors that conserve energy) is an effective way to manage metabolic disorders, such as obesity and Type-2 Diabetes.

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Countering the Modern Metabolic Disease Rampage With Ancestral Endocannabinoid System Alignment Download

This paper is also stored here: http://bit.ly/31rATuL inside the CED Foundation Archive

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Dr Caplan & Dr Grinspoon meet with Wiley’s Alcohol and Drug Abuse Weekly

June 11, 2019 Cannabis Education, Cannabis News, Cannabis Science, CED In The News, Dr Caplan, Dr Grinspoon, Future Medicine, News, Science, Social Equity, Social Justice

It was a privilege to meet with the editor of Wiley Publishing Company’s Alcohol and Drug Abuse Weekly, Dr Peter Grinspoon, and a select group of MA dispensary representatives this weekend, to discuss our shared goals & plan to support global access to education, of physicians, the #MedicalCommunity, the #CannabisIndustry, and the #CannabisCommunity.

Alcohol Hangover Has Detrimental Impact Upon Both Executive Function and Prospective Memory

June 11, 2019 Abuse, Alcohol, Behavior change, Cannabis, Cannabis Education, Cannabis Science, Cognition, Concussion, Depression, Driving, Future Medicine, Memory, Mental Health, Mood, Muscle Pain, Occasional Use, Pain, Products, Science, Sleep, Social Justice, Stress, THC, Welfare

In a study that excluded cannabis users, researchers found that alcohol hangovers significantly impair both executive function (paying attention, regulating emotions, etc.) and prospective memory (remembering future plans).

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Alcohol Hangover Has Detrimental Impact Upon Both Executive Function and Prospective Memory Download

This paper is also stored here: http://bit.ly/31paJsL inside the CED Foundation Archive

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Multiple Health Risk Behaviors in Young Adult Smokers: Stages of Change and Stability over Time

June 11, 2019 Adolescents, Adverse Effects, Behavior change, Cannabis, Cannabis Education, Cannabis Science, Citizen Science, Future Medicine, Heavy Use, History, Occasional Use, Pediatrics, Science, Social Justice, Survey, THC

Study finds that most young adult smokers engage in multiple other health risk behaviors. When placed in an intervention, participants were most ready to change their stress management and least ready to change their cannabis use.

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Multiple Health Risk Behaviors in Young Adult Smokers- Stages of Change and Stability over Time Download

This paper is also stored here: http://bit.ly/31mTqIM inside the CED Foundation Archive

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Video: Cannabis For Symptoms of chronic pain, seizures, and inflammation

June 10, 2019 Adverse Effects, Anti-inflammatory properties, Anxiety, Arthritis, Cannabinoids, Cannabis, Cannabis Education, Cannabis News, Cannabis Science, CB1, CB2, CBD, Citizen Science, Depression, Dronabinol, Elderly, Flavonoids, Future Medicine, Heavy Use, History, IBS, Insomnia, Neuropathy, Occasional Use, Opiates, Overdose, Pain, Psychosis, Schizophrenia, Science, Sleep, Stigma, THC, Withdrawal

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Preferences for Medical Marijuana over Prescription Medications Among Persons Living with Chronic Conditions- Alternative, Complementary, and Tapering Uses Download

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Synthetic Cannabinoids Provide Evidence for Targeting Cannabinoid Receptors in the Treatment of Autoimmune Diseases

June 10, 2019 Anti-inflammatory properties, Arthritis, Autoimmunity, Cannabinoids, Cannabis Science, CB1, CB2, Future Medicine, Muscle Pain, Neuropathy, Science, Synthetic Cannabinoids

Pharmaceutical Cannabis Derivatives Help Discover their Receptors and Functions for Autoimmune Illnesses

A recent study conducted by Michigan State University exposed the potential for cannabinoid receptor 2 (CB2) to target the treatment of inflammatory conditions. Elevated levels of plasmacytoid dendritic cells (pCD, a type of cell in the immune system) contribute to chronic inflammation in autoimmune diseases, such as Rheumatoid Arthritis. Researchers found that synthetic CB2 agonists reported comparable benefits to THC, but minimized the cerebral effects as the psychotropic activity is mediated by cannabinoid receptor 1 (CB1). This evidence demonstrates the potential benefits of CB2-targeted treatment for inflammatory conditions. Unfortunately, there are serious concerns about the misuse of some synthetic cannabinoids, so there is still a missing bridge, in products and public education, between these research products and potential therapeutic pharmaceuticals, down the road.

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Suppression of CpG-ODN-mediated IFNα and TNFα response in human plasmacytoid dendritic cells (pDC) by cannabinoid receptor 2 (CB2)-specific agonists Download

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Medical Marijuana Confers Benefits Comparable to Prescription Medication, Without the Side Effects

June 10, 2019 Adverse Effects, Anxiety, Arthritis, Cannabinoids, Cannabis, Cannabis Education, Cannabis Science, CBD, Citizen Science, DSM-5, Future Medicine, History, Insomnia, Occasional Use, Opiates, Pain, Science, Survey, THC

Preferences for Medical Marijuana over Prescription Medications Among Persons Living with Chronic Conditions: Alternative, Complementary, and Tapering Uses

In a survey of 30 patients using medical cannabis for a range of illnesses, including Rheumatoid Arthritis, cancer, Hepatitis C, PTSD, and more, patients reported an array of benefits from their cannabis use. Patients successfully used cannabis as an alternative to prescription medication, as a complementary agent with traditional prescription medicines, and to gradually help halt the use of some prescription medications. Benefits described by participants included the effects of cannabis lasting longer than that of opioids, lower risk of addiction, fewer side-effects. Patients also saw their sleep, anxiety, appetite, and adverse reactions improve with the use of medical cannabis. Larger, more controlled studies may suggest cannabis more affirmatively as an alternative or complementary therapy with prescription medications.

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Preferences for Medical Marijuana over Prescription Medications Among Persons Living with Chronic Conditions- Alternative, Complementary, and Tapering Uses Download

This paper is also stored here: http://bit.ly/2wqDDdQ inside the CED Foundation Archive

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Some, But Not Enough Data on Cannabis for Chronic Pain

June 10, 2019 Arthritis, Cannabinoids, Cannabis, Cannabis Education, Cannabis Science, CB1, CB2, CBD, Future Medicine, Muscle Pain, Neuropathy, Pain, Science, THC

Overlaps in pharmacology for the treatment of chronic pain and mental health disorders

Select small trials have demonstrated cannabis to be more effective than other analgesics to treat chronic pain associated with certain conditions. However, the existing research lacks large-scale, controlled experiments relating medical cannabis use to pain management. Additionally, negative effects are documented with respect to cannabis use among adolescents and those suffering from compromised mental health. There is a need for further research on the topic.

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Overlaps in pharmacology for the treatment of chronic pain and mental health disorders Download

This paper is also stored here: http://bit.ly/2wtvpRY inside the CED Foundation Archive

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Cannabis and Cavities, Delta-3-Carene

June 8, 2019 Adverse Effects, Cannabis, Cannabis Science, Delta-3-Carene, Oral Health, Science, Taste

Dentists’ concerns about the negative effects of cannabis on teeth are legitimate: dry mouth can lead to cavities. It is known that the terpene Delta-3-Carene can dry out bodily fluids (saliva), so avoiding strains w/ high levels can help. http://bit.ly/2KFpp0K

Video: Medical Marijuana: What Physicians Need to Know

June 6, 2019 Autoimmunity, Cancer, Cannabinoids, Cannabis, Cannabis Education, Cannabis Science, CB1, CB2, CBD, Extraction, Flavonoids, Future Medicine, IBS, Insomnia, Multiple Sclerosis, Muscle Pain, Neuropathy, Science, Sleep, Terpenes, THC, Video

A video adaptation of “Medical Marijuana: What Physicians Need to Know”

Medical_Marijuana_What_Physicians_Need_to_Know Download

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