All posts tagged: Adolescents

Cost-effectiveness of treating pediatric drug-resistant epilepsy

Cannabis-based treatments may reduce seizures among children with drug-resistant epilepsy, but are these treatments cost-effective? 

Economic evaluations of cannabis treatments are needed, and they should address issues including weight-gain over time, switching or discontinuation of treatments, the effectiveness of interventions, and long-term success, beyond the duration of available clinical studies.

This paper is also stored here:     http://bit.ly/2INWAOJ    inside the CED Foundation Archive

To explore related information, click the keywords below:

Benjamin Caplan, MDCost-effectiveness of treating pediatric drug-resistant epilepsy
read more

Analyses of Cannabinoid Signaling in the Immune System Highlights Key Questions, Challenges, and Future Directions

Targeting Cannabinoid Signaling in the Immune System: “High”-ly Exciting Questions, Possibilities, and Challenges

A meta-analysis concerning the role of cannabinoid signaling in immune system regulations revealed current therapeutic benefits, challenges for future research, and exciting new directions. Among the current research, cannabinoids have already been found to suppress inflammation associated with autoimmune diseases, especially in multiple sclerosis, rheumatoid arthritis, Type-1 Diabetes, and Crohn’s Disease. Future cannabis-based therapies aim to improve immune responses to organ donation, bone marrow transplants, and skin grafts. The analysis includes challenges facing future cannabis research such as potential side effects and legal status.  

View this review (yellow link) or download:

This paper is also stored here:    http://bit.ly/31ArGR9      inside the CED Foundation Archive

To explore related information, click the keywords below:

Benjamin Caplan, MDAnalyses of Cannabinoid Signaling in the Immune System Highlights Key Questions, Challenges, and Future Directions
read more

Variations in Genes Influences Cannabis’ Acute Effects on Behavior

CNR1 and FAAH variation and affective states induced by marijuana smoking

A recent study has revealed that variations within cannabinoid receptor 1 (CBR1) and fatty acid amide hydrolase (FAAH) influences cannabis’ acute effects on affect. Variations of CBR1 and FAAH are known to be associated with cannabis dependence. The current study now adds that the variations in genes also affect an individual’s behavior when ingesting cannabis. The results of this study provide useful information for understanding an individual’s motivation for marijuana use, as well as risks and associated behaviors.

View this review (yellow link) or download:

This paper is also stored here:   http://bit.ly/31Ce9Za     inside the CED Foundation Archive

To explore related information, click the keywords below:

Benjamin Caplan, MDVariations in Genes Influences Cannabis’ Acute Effects on Behavior
read more

Vaping cannabis among adolescents: prevalence and associations with tobacco use from a cross-sectional study in the USA

Out of 2,835 high school students from North Carolina, 272 students (or 9.6%) reported ever vaping cannabis. Interestingly, the odds of ever vaping cannabis were significantly higher among males (11.0%) compared with females (8.2%), and significantly higher among non-Hispanic white students (11.3%) compared with non-Hispanic black students (5.0%).

It’s clear that white males are the most likely to have ever vaping cannabis. Why might minority students engage less with recreational drug use?

View this review (yellow link) or download:

This paper is also stored here:    http://bit.ly/2L6zYdv     inside the CED Foundation Archive

Benjamin Caplan, MDVaping cannabis among adolescents: prevalence and associations with tobacco use from a cross-sectional study in the USA
read more

Cannabinoid Receptors Working with Opioid Receptors

The locus coeruleus is a spot in the human brainstem that is integral to our responses to stress, panic, wakefulness, and sleep-wake transitions. Both the cannabinoid receptors and opioid receptors in the locus coeruleus have a synergistic relationship that, once the medical system begins to incorporate more education about cannabinoids, just might change how physicians prescribe pain medication. The interactions of the two receptor types provide a mechanism that could easily and conveniently improve pain control, provide treatments for addiction, and will likely aid those experiencing symptoms of withdrawal. Research focusing on the treatment of opioid addiction with cannabis is ongoing… but hindered by the legal status of cannabis.

View this review (yellow link) or download:

This paper is also stored here:     http://bit.ly/2MMeYeK    inside the CED Foundation Archive

To explore related information, click the keywords below:

Benjamin Caplan, MDCannabinoid Receptors Working with Opioid Receptors
read more

Capsaicin Cream Treats Cannabinoid Hyperemesis Syndrome in Adolescents

Capsaicin Cream for Treatment of CHS adolescent

Researchers have found that capsaicin cream is an effective and safe method of treating cannabinoid hyperemesis syndrome (CHS) in adolescents. Capsaicin cream has previously been shown to be effective at treating CHS in adults but adolescents have previously been treated with haloperidol, a drug known to have serious side effects. Capsaicin cream offers a much safer and more cost-effective method of treatment for adolescents.

View this review (yellow link) or download:

This paper is also stored here:   http://bit.ly/2F8Gtcc      inside the CED Foundation Archive

To explore related information, click the keywords below:

Benjamin Caplan, MDCapsaicin Cream Treats Cannabinoid Hyperemesis Syndrome in Adolescents
read more

Adolescent Executive Dysfunction in Daily Life: Relationships to Risks, Brain Structure and Substance Use

Researchers assessed 817 youth (aged 12 to 21) who previously participated in the National Consortium on Alcohol and Neurodevelopment in Adolescence study. They found that 123 subjects (15.2%) had used cannabis in the past year, and that cannabis use impaired inhibitory control, emotional control, and task planning.

View this review (yellow link) or download:

This paper is also stored here:    http://bit.ly/2L0aMWa     inside the CED Foundation Archive

Benjamin Caplan, MDAdolescent Executive Dysfunction in Daily Life: Relationships to Risks, Brain Structure and Substance Use
read more

Medical Marijuana and Treatment of Pediatric Epilepsy Patients

Medical Marijuana in the Pediatric Population With Epilepsy—What You Should Know

A recent review has discussed the known benefits of treating children who are suffering from epilepsy with cannabis-based medicine. Medical marijuana (MM) is a viable option for treating this population that comes with risks due to the high that comes from THC and its legal status as a Schedule 1 drug. The legal status is currently preventing larger scale research to be done so that physicians can better educate parents on how to care for a child taking MM.

View this review (yellow link) or download:

This paper is also stored here:     http://bit.ly/2KNbGVS    inside the CED Foundation Archive

To explore related information, click the keywords below:

Benjamin Caplan, MDMedical Marijuana and Treatment of Pediatric Epilepsy Patients
read more

How to prevent inappropriate teen use?

Especially in Colorado and Washington, people are taking note of teens’ use and access to potent marijuana, and many are concerned that there are not enough measures in place to prevent this. Newly legalized states should look into this before it becomes a national issue. https://wapo.st/2Fgmto9

Benjamin Caplan, MDHow to prevent inappropriate teen use?
read more

The Education of Dispensary Staff is Varied and Lacks Regulation

Training and Practices of Cannabis Dispensary Staff

How much medical training does your local budtender possess? An online survey sent to medical marijuana dispensary staff reported only 55% of staffers had any formal training for their position, with 20% reporting some background in medical/scientific training. The analysis reported that many among the dispensary staff are recommending cannabis choices that are consistent with current evidence, but some are recommending strains that are either ineffective or exacerbate a patient’s condition. The findings of this study stress the importance of consistent and well-regulated training of dispensary staff.

View this review (yellow link) or download:

This paper is also stored here:    http://bit.ly/2FfJNSC     inside the CED Foundation Archive

To explore related information, click the keywords below:

Benjamin Caplan, MDThe Education of Dispensary Staff is Varied and Lacks Regulation
read more