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Some, But Not Enough Data on Cannabis for Chronic Pain

June 10, 2019 , , , , , , , , , , , , ,

Overlaps in pharmacology for the treatment of chronic pain and mental health disorders

Select small trials have demonstrated cannabis to be more effective than other analgesics to treat chronic pain associated with certain conditions. However, the existing research lacks large-scale, controlled experiments relating medical cannabis use to pain management. Additionally, negative effects are documented with respect to cannabis use among adolescents and those suffering from compromised mental health. There is a need for further research on the topic.

View this review (yellow link) or download:

Overlaps in pharmacology for the treatment of chronic pain and mental health disordersDownload

This paper is also stored here: http://bit.ly/2wtvpRY inside the CED Foundation Archive

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Benjamin Caplan, MDSome, But Not Enough Data on Cannabis for Chronic Pain
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Misleading Headlines of THC “overdose”

June 7, 2019 , , , , , ,

Misleading headlines make it seem like this woman may have died of THC overdose, however, we know that it would be nearly impossible to consume lethal amounts of THC, and the coroner clearly made vague, and incomplete assumptions. This, likely feeding into a comfortable, though quite false stigma around cannabis. http://bit.ly/31iwwlK

Benjamin Caplan, MDMisleading Headlines of THC “overdose”
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Video: Medical Marijuana: What Physicians Need to Know

June 6, 2019 , , , , , , , , , , , , , , , , , , , , ,

A video adaptation of “Medical Marijuana: What Physicians Need to Know”

Medical_Marijuana_What_Physicians_Need_to_KnowDownload

This paper is also stored here:   (http://bit.ly/2KxqoAe)      inside the CED Foundation Archive

To explore related information, click the keywords below:

Benjamin Caplan, MDVideo: Medical Marijuana: What Physicians Need to Know
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Sativex Reduces MS-Related Spasticity

June 5, 2019 , , , , ,

Delta-9-Tetrahydrocannabidiol Oromucosal Spray (Sativex): A Review in Multiple Sclerosis-Related Spasticity

A debilitating symptom of multiple sclerosis (MS) is spasticity, the stiffness and involuntary spasms of muscles, often occurring in the legs. In a randomized study involving MS patients who have not experienced relief with any current anti-spasticity medication, Sativex, a THC/CBD oro-mucosal spray was administered. Patients receiving THC/CBD experienced significantly more spasticity relief than the placebo group. Sativex may hold substantial treatment potential for MS patients, as side effects are minimized, the spray allows for an adjustable dosage, and there is low potential for abuse.

While this pharmaceutical is proving to be effective, in related data, we also see a distinct advantage of non-pharmaceutical options, including cost, availability, and efficacy, although drastically higher variability and limited consistency in product.

http://bit.ly/2WwVoqA

Benjamin Caplan, MDSativex Reduces MS-Related Spasticity
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Medical Cannabis: Vaping Over Other Delivery Options

June 4, 2019 , , ,

Medical cannabis users prefer vaping for fast, portable, discrete treatment

Previous research shows that medical cannabis users prefer vaporization, or vaping, as a means for drug administration. In a Brown University study, 25 consumers of medical cannabis were surveyed to further investigate this phenomenon. Participants largely preferred vaping over other forms of delivery. Patients cite increased cost efficiency, discrete use, more ease in transporting medication when traveling, and more immediate symptom relief as reasons for this preference. Based on these data, vaping may be a valuable drug delivery option for cannabis users seeking a discrete, portable, effective treatment vehicle. bit.ly/2W378N3

Benjamin Caplan, MDMedical Cannabis: Vaping Over Other Delivery Options
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Entourage Effect & Alzheimer’s Disease

May 31, 2019 , ,

Research about the “entourage effect” of cannabinoids has led to potential treatments of neurodegenerative diseases such as Alzheimer’s Disease. For example, ingesting CBD along with THC not only dulls the intoxicating effects but can lead to a smoother effect rather than an experience of peaks and troughs. http://bit.ly/2W1zAPk

Benjamin Caplan, MDEntourage Effect & Alzheimer’s Disease
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