Cannabis

Video: Cannabis For Symptoms of chronic pain, seizures, and inflammation

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Benjamin Caplan, MDVideo: Cannabis For Symptoms of chronic pain, seizures, and inflammation
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Medical Marijuana Confers Benefits Comparable to Prescription Medication, Without the Side Effects

Preferences for Medical Marijuana over Prescription Medications Among Persons Living with Chronic Conditions: Alternative, Complementary, and Tapering Uses

In a survey of 30 patients using medical cannabis for a range of illnesses, including Rheumatoid Arthritis, cancer, Hepatitis C, PTSD, and more, patients reported an array of benefits from their cannabis use. Patients successfully used cannabis as an alternative to prescription medication, as a complementary agent with traditional prescription medicines, and to gradually help halt the use of some prescription medications. Benefits described by participants included the effects of cannabis lasting longer than that of opioids, lower risk of addiction, fewer side-effects. Patients also saw their sleep, anxiety, appetite, and adverse reactions improve with the use of medical cannabis. Larger, more controlled studies may suggest cannabis more affirmatively as an alternative or complementary therapy with prescription medications.

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This paper is also stored here:   http://bit.ly/2wqDDdQ      inside the CED Foundation Archive


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Benjamin Caplan, MDMedical Marijuana Confers Benefits Comparable to Prescription Medication, Without the Side Effects
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Some, But Not Enough Data on Cannabis for Chronic Pain

Overlaps in pharmacology for the treatment of chronic pain and mental health disorders

Select small trials have demonstrated cannabis to be more effective than other analgesics to treat chronic pain associated with certain conditions. However, the existing research lacks large-scale, controlled experiments relating medical cannabis use to pain management. Additionally, negative effects are documented with respect to cannabis use among adolescents and those suffering from compromised mental health. There is a need for further research on the topic.

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This paper is also stored here: http://bit.ly/2wtvpRY inside the CED Foundation Archive

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Benjamin Caplan, MDSome, But Not Enough Data on Cannabis for Chronic Pain
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Teens Regularly Consuming Cannabis More Likely to Have Suffered Sexual Abuse

Identifying teenage sexual abuse victims by questions on their daily lives

According to the World Health Association, approximately 13.4% of girls and 5.7% of boys experience child sexual abuse. Victims of child sexual abuse are more prone to, among other negative health and social outcomes, increased consumption of cannabis as teens. Teens who have been a victim to child sexual abuse are significantly more likely to participate in regular cannabis consumption than their non-sexually abused counterparts. Given its status as an international public health problem, further research needs to be completed to determine appropriate therapeutic plans for victims of child sexual abuse in order to reduce their increased odds of negative mental, physical, and emotional outcomes.

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This paper is also stored here: http://bit.ly/2YZDREV inside the CED Foundation Archive

Benjamin Caplan, MDTeens Regularly Consuming Cannabis More Likely to Have Suffered Sexual Abuse
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Guanfacine reducing cannabis withdrawal symptoms?

Guanfacine decreases symptoms of cannabis withdrawal in daily cannabis smokers

A study performed on daily cannabis users with cannabis use disorder (CUD) found evidence for Guanfacine to reduce the irritability and disturbances to sleep, characteristic of cannabis withdrawal. It is potentially a viable, improved alternative to Lofexidine, another treatment for CUD which happens to result in some adverse effects, including drowsiness, dizziness, and altered food intake. However, beyond these effects, while Lofexidine reduced cannabis self-administration following abstinence, Guanfacine did not in this study. Regardless, further research on the therapeutic effects of Guanfacine may be worthwhile and could help reduce cannabis cravings following withdrawal.

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This paper is also stored here: http://bit.ly/2wsKbZh inside the CED Foundation Archive

Benjamin Caplan, MDGuanfacine reducing cannabis withdrawal symptoms?
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Misleading Headlines of THC “overdose”

Misleading headlines make it seem like this woman may have died of THC overdose, however, we know that it would be nearly impossible to consume lethal amounts of THC, and the coroner clearly made vague, and incomplete assumptions. This, likely feeding into a comfortable, though quite false stigma around cannabis. http://bit.ly/31iwwlK

Benjamin Caplan, MDMisleading Headlines of THC “overdose”
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A theory for a presidential candidate to de-schedule cannabis

One 2020 candidate recognizes the judicial, medical, and economic effects of cannabis prohibition and has laid out a plan to end it. Gillibrand (D-NY) plans to not only de-schedule cannabis but expunge criminal records and boost medical research while harnessing economic opportunities http://bit.ly/31iuNwM

Benjamin Caplan, MDA theory for a presidential candidate to de-schedule cannabis
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Producing the ‘problem’ of new psychoactive substances (NPS) in English prisons

The use of synthetic cannabinoids in English prisons is currently considered a “law, order and control” problem, with associated regulation and penalties. There is a clear and problematic disconnect between prison administrators and users. Resources for education, training and work opportunities are missing.

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Benjamin Caplan, MDProducing the ‘problem’ of new psychoactive substances (NPS) in English prisons
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Cannabinoid receptors as therapeutic targets for autoimmune diseases: where do we stand?

Because of the associated anti-inflammatory action, modulation of CB1R & CB2R is helpful to treat autoimmune diseases, including Multiple Sclerosis, Type-1 Diabetes Mellitus, and Rheumatoid Arthritis The full list is truly very much longer, as every illness necessarily involves the immune system and cellular communication.

The following review, written by Elaine D. Gonc ̧alves

The following review, written by Daphna Katz-Talmor: (yes, same name, unfortunately!)

Benjamin Caplan, MDCannabinoid receptors as therapeutic targets for autoimmune diseases: where do we stand?
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