Benjamin Caplan, MD

Misleading Headlines of THC “overdose”

Misleading headlines make it seem like this woman may have died of THC overdose, however, we know that it would be nearly impossible to consume lethal amounts of THC, and the coroner clearly made vague, and incomplete assumptions. This, likely feeding into a comfortable, though quite false stigma around cannabis. http://bit.ly/31iwwlK

Benjamin Caplan, MDMisleading Headlines of THC “overdose”
read more

A theory for a presidential candidate to de-schedule cannabis

One 2020 candidate recognizes the judicial, medical, and economic effects of cannabis prohibition and has laid out a plan to end it. Gillibrand (D-NY) plans to not only de-schedule cannabis but expunge criminal records and boost medical research while harnessing economic opportunities http://bit.ly/31iuNwM

Benjamin Caplan, MDA theory for a presidential candidate to de-schedule cannabis
read more

Producing the ‘problem’ of new psychoactive substances (NPS) in English prisons

The use of synthetic cannabinoids in English prisons is currently considered a “law, order and control” problem, with associated regulation and penalties. There is a clear and problematic disconnect between prison administrators and users. Resources for education, training and work opportunities are missing.

For the full review:

Benjamin Caplan, MDProducing the ‘problem’ of new psychoactive substances (NPS) in English prisons
read more

Cannabinoid receptors as therapeutic targets for autoimmune diseases: where do we stand?

Because of the associated anti-inflammatory action, modulation of CB1R & CB2R is helpful to treat autoimmune diseases, including Multiple Sclerosis, Type-1 Diabetes Mellitus, and Rheumatoid Arthritis The full list is truly very much longer, as every illness necessarily involves the immune system and cellular communication.

The following review, written by Elaine D. Gonc ̧alves

The following review, written by Daphna Katz-Talmor: (yes, same name, unfortunately!)

Benjamin Caplan, MDCannabinoid receptors as therapeutic targets for autoimmune diseases: where do we stand?
read more

Adolescent Cannabis Use Can Impact Sleep Habits

Exploring Interventions for Sleep Disorders in Adolescent Cannabis Users

The effects of cannabis on sleep are varied and dependent on dosage and the component of cannabis in question. For instance, low doses of cannabidiol (CBD) have an energizing effect, while higher doses can prompt drowsiness. Cannabis use among adolescents results in similar although occasionally more pronounced effects on sleep than among adults. Previous studies have reported a relationship between cannabis use and an individual’s “sleep duration, self-reported sleep problems, and insomnia.” Furthermore, many newcomers to cannabis approach the plant as an aid to sleep, and regular cannabis use may result. This may lead to an increase in tolerance and, upon attempts to quit, a disruption in sleep and REM may rebound. At a time when sleep is crucial to development, considering the wide field of unknowns and potential impact, adolescents should proceed cautiously, and with restraint, when consuming cannabis.

http://bit.ly/2KfJYky

Benjamin Caplan, MDAdolescent Cannabis Use Can Impact Sleep Habits
read more

A selective CB2 agonist protects against the inflammatory response and joint destruction in collagen-induced arthritis mice

In a study of 40 mice, scientists find that the CB2-selective agonist significantly reduced the severity of arthritis and markedly reduced bone erosion. These data clearly indicate that the CB2-selective agonist may be considered a novel treatment for rheumatoid arthritis.

Benjamin Caplan, MDA selective CB2 agonist protects against the inflammatory response and joint destruction in collagen-induced arthritis mice
read more

Ruth Fisher’s Cannabis Primer Book

Ruth Fisher, PhD (https://www.linkedin.com/in/rfisher/) published a wonderful compilation of introductory cannabis info, rich summaries of cannabis literature, wrapped nicely in a gorgeous soft cover layout, and stunning photography. 2 thumbs up for “The Medical Cannabis Primer” !
https://www.amazon.com/dp/1885176023/ref=cm_sw_em_r_mt_dp_U_INN-CbM5F06HA

Benjamin Caplan, MDRuth Fisher’s Cannabis Primer Book
read more

Market Projections, Ethanol Extraction, and Mismatched Expectations

While most people tout market projections, this CEO notes that many people entering the industry have not considered the logistics behind creating and expanding their business. In such a unique industry, realistic goals and measures will be crucial to long term success and scaling. http://bit.ly/31fJYH0

Benjamin Caplan, MDMarket Projections, Ethanol Extraction, and Mismatched Expectations
read more