Benjamin Caplan, MD

Ben

Compounds in Citrus Peels Functioning as Preventive Agents for Prostate Cancer

June 15, 2019 Anti-inflammatory properties, Autoimmunity, Blood-Levels, Cancer, Cannabis, Cannabis Education, Cannabis Science, Extraction, Flavonoids, Future Medicine, Non-Cannabis Plant, Processing, Science, Terpenes

Effect of citrus peel extracts on the cellular quiescence of prostate cancer cells

A recent study has revealed that citrus peel extracts (CPE) have the potential to prevent prostate cancer from recurring in post-therapy cancer patients. A component of CPE, flavonoids, have previously been found to have anticancer effects, but appear to lack the correct structure to prevent tumors in patients with prostate cancer. This specific study found that the citric acid present in CPE was the contributing factor to its anticancer effects but mentioned that flavonoids should continue to be researched for chemopreventive benefits.

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Effect of citrus peel extracts on the cellular quiescence of prostate cancer cells Download

This paper is also stored here: http://bit.ly/2KMVxzK inside the CED Foundation Archive

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Cognitive Function in Aging Cocaine Smokers is Marginally Lower than Controls

June 15, 2019 Abuse, Adverse Effects, Aging, Behavior change, Cocaine, Cognition, DSM-5, Elderly, Heavy Use, Memory, Occasional Use, Placebo-Controlled, Products, Science

Cognitive function in aging cocaine smokers

A recently published study looking to expose the functional status of older drug users has found that most of their cognitive abilities are equal to their peers who have never smoked cocaine, except for a marginally lower verbal comprehension. Similar studies should continue in order to determine how chronic drug users will affect or challenge public health systems in the future.

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Cognitive function in aging cocaine smokers Download

This paper is also stored here: http://bit.ly/2FbOUmZ inside the CED Foundation Archive

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High-potency cannabis and incident psychosis: correcting the causal assumption

June 15, 2019 Adverse Effects, Anxiety, Behavior change, Cannabinoids, Cannabis, Cannabis Education, Cannabis News, CB1, CB2, CBD, Cognition, DSM-5, Hypomania, Mental Health, Psychosis, Schizophrenia, THC

Scientists offer a strong counter-position to the belief that cannabis causes psychosis, pointing out the difference between correlation and causation. They argue that smoke exposure from any source (including cigarettes) could explain the reported link between cannabis and psychosis.

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High-potency cannabis and incident psychosis- correcting the causal assumption Download

This paper is also stored here: http://bit.ly/2WHtDr8 inside the CED Foundation Archive

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Treating insomnia with cannabis

June 14, 2019 Cannabinoids, Cannabis, Cannabis News, Cannabis Science, CBD, Future Medicine, Insomnia, REM Sleep, Science, Sleep, Sleep Apnea, THC

Many people use cannabis to treat insomnia, as THC has proven effects. What about CBD? There are no clear, incontrovertible studies, and effects differ by the user, but there are promising results. More noticeably, certain terpenes have been shown to be quite effective, for example, Myrcene. http://bit.ly/2F9PXUp

Common Concerns for cannabis CEOs

June 14, 2019 Cannabis News, Dispensaries, History, Legislation, News, Products, Regulation

When the CEOs of major cannabis companies were asked what they believed the biggest threats to the cannabis industry are, the answers were consistent with common concerns: black market cannabis, public policy, execution of businesses, as well as consistency of product and markets. Not only in the US, but also globally https://yhoo.it/31pNOO9

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News: Medical dispensaries vs Recreational

June 14, 2019 Cannabis News, Dispensaries, Law, Legislation, News, Regulation, Social Equity

As more states begin to legalize cannabis recreationally, the number of medical patients drops rapidly. Higher costs, fewer shops, and the removal of some products for ones with a wider appeal can make it difficult for patients to get the medication they have been relying on. http://bit.ly/31slU3Y

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Flavonoids May Provide Therapeutic Benefits for Type 2 Diabetes

June 14, 2019 Anti-inflammatory properties, Autoimmunity, Cannabis, Cannabis Education, Cannabis Science, CB1, CB2, CBD, Diabetes, Extraction, Flavonoids, Future Medicine, Non-Cannabis Plant, Placebo-Controlled, Processing, Products, Science

A recent study has found that flavonoids isolated from Psoralea corylifolia are able to inhibit part of the insulin pathway.

Seeds of the P. corylifolia plant have been used in eastern medicine, primary in China, for years, and is now being further researched as flavonoids continue to intrigue researchers with their possible therapeutic benefits. The inhibitory activity found in this study provides evidence that flavonoids should be pursued as a potential treatment for Type-2 Diabetes.

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New compounds from the seeds of Psoralea Corylifolia with their protein tyrosine phosphatase 1B inhibitory activity Download

This paper is also stored here: http://bit.ly/2KORB1v inside the CED Foundation Archive

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New Extraction Methods for “Polyphenols” Benefits Future Research

June 14, 2019 Anti-inflammatory properties, Cannabinoids, Cannabis, Cannabis Education, Cannabis Science, CB1, CB2, CBD, Diabetes, Extraction, Flavonoids, Future Medicine, Obesity, Processing, Science, Terpenes

Citrus peels waste as a source of value-added compounds- extraction and quantification of bioactive polyphenols

A recent study has exposed a more efficient, sustainable, and economically viable extraction method for polyphenols (specific active chemical compounds) from citrus peels. One such polyphenol is Naringin, a flavonoid present in lemon peels, which has been hypothesized to have anti-inflammatory and antioxidant effects, as well as, potentially, to help treat obesity. This new extraction method will allow researchers to discover more definite therapeutic effects of polyphenols in citrus peels.

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Citrus peels waste as a source of value-added compounds- extraction and quantification of bioactive polyphenols Download

This paper is also stored here: http://bit.ly/2F7XrXY inside the CED Foundation Archive

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Cannabidiol (CBD) as an Adjunctive Therapy in Schizophrenia: A Multicenter Randomized Controlled Trial

June 14, 2019 Anxiety, Behavior change, Cannabinoids, Cannabis, Cannabis Science, CB1, CB2, CBD, DSM-5, Future Medicine, Mental Health, Placebo-Controlled, Science

A 2018 study showed that, for patients with schizophrenia, adding CBD to ongoing antipsychotic treatment reduced psychotic activity, as compared to placebo add-on